Skip to content
Reserved for aesthetic medicine professionals.
GleySy
Contact
All articles
8 November 2026

Hydration is no longer enough. Skin demands duration.

Capturing water is simple. Holding it is a matter of molecular architecture. The GleySy® multi-fraction hyaluronic acid synergy, fraction by fraction.

Gouttelettes d'eau et structures moléculaires translucides — l'univers de l'hydratation longue durée GleySy®
Skin never lacks water. It lacks what holds it.

Hydration is the first step of professional care, and the one most often reduced to its simplest expression: supplying water. Yet skin is not judged in the moment that follows a treatment. It is judged three days later.

Everything in between comes down to structure. Capturing water is easy. Holding it, organising it, releasing it over hours calls for a molecular architecture built for the task.

That architecture is what GleySy® has worked on from the start, under one name: multi-fraction hyaluronic acid synergy.

One molecule, many chain lengths

Hyaluronic acid is not a molecule: it is a family. A single INCI name covers chains of very different lengths, measured in daltons, from a fragment of a few hundred daltons to a polymer of several million.

That length is no manufacturing detail. It governs how the chain behaves: its mobility, the level at which it sits, the volume of water it structures and how long it does so.

  • Low-molecular-weight fractions are mobile and diffusing.
  • High-molecular-weight fractions structure water at the surface and deliver immediate comfort.
  • Cross-linked structures resist natural enzymatic degradation for longer.

A formulation built on a single chain length therefore plays in one register only. It hydrates — in the singular.

Multi-fraction hyaluronic acid synergy

The GleySy® approach brings together, within one formula, several hyaluronic acid fractions chosen for how they complement one another — not for how many they are.

Each fraction occupies its own level. Their assembly does not aim at a peak of hydration: it aims at continuity. The most mobile fractions open the way, the longest hold the duration.

One fraction gives a moment. Several coordinated fractions give a duration.

The detail of that assembly belongs to the laboratory. What is visible is the logic governing it: every molecular weight must have a reason to be there, and only one.

HYAL PURE — hyaluronic acid, and nothing else

With HYAL PURE, GleySy® demonstrates multi-fraction synergy in its most pared-back state: hyaluronic acid, with no supporting active lending its name to the result.

Two concentrations answer two protocol intentions: Hyal Pure 1% for sustained work on skin quality, Hyal Pure 2% when the practitioner is seeking reinforced hydration. The level is chosen by protocol, not by default.

Its signature: mastery of a formula with nothing to hide behind a star ingredient.

Hyal Pure 1% GleySy® — Hyaluronic acid — Box of 5 × 10 mlHyaluronic acidHyal Pure 1%Professional hyaluronic acid solution.Discover HYAL PURE 1%

RICH PDRN — hydration backed by biotechnology

RICH PDRN combines Sodium DNA — PDRN nucleotides — with amino acids, L-lactic acid and hyaluronic acid. Hydration is not an isolated objective here: it is the medium in which the other actives work.

That is the difference between watering and preparing ground. A properly hydrated dermis is one where what comes next finds its place.

PDRN and peptides now have an article of their own: the new intelligence of professional skincare.

Its signature: hydration used as a foundation, not as a promise.

Rich PDRN GleySy® — PDRN complex — Box of 5 × 10 mlPDRN complexRich PDRNProfessional complex combining Sodium DNA, amino acids, lactic acid and hyaluronic acid.Discover RICH PDRN

RICH BTX — duration on expression areas

RICH BTX brings together neuropeptides and hyaluronic acid. Expression areas — forehead, eye contour, folds — are where water loss shows fastest, because they move.

Pairing hyaluronic acid with peptides there is a matter of formulation coherence: supple skin holds over time better than dry skin, however precise the rest of the formula.

A cosmetic peptide formulation: its action is not comparable to that of a botulinum toxin injection and makes no claim to replace it.

Its signature: smoothness and hydration designed into the same formula, not one after the other.

Rich BTX GleySy® — Peptide complex — Box of 5 × 5 mlPeptide complexRich BTXProfessional complex of peptides and hyaluronic acid.Discover RICH BTX

Cross-linked structure, or duration as a formulation criterion

Beyond free chains, cross-linking — chains bound to one another in a network — changes the nature of the problem. A network degrades more slowly than an isolated chain: duration stops being a consequence and becomes a formulation parameter.

GleySy® puts that principle to work in LiftDerm, where a Sodium Hyaluronate Crosspolymer completes the free fractions. The two registers do not replace one another: they take over from one another.

Hydrating is not a step, it is a line

In-practice care establishes the supply. Daily care holds it. Between the two, continuity of formulation makes the difference between a result visible that evening and a result that settles.

The same requirement governs the professional peel range: the science of peeling — another range, a single formulation method.

GleySy® hydration is not measured at the moment of the treatment. It is measured by what remains of it.

Discover the Mesotherapy range