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7 November 2026

The new intelligence of professional skincare: PDRN, peptides and precision actives

PDRN, biomimetic peptides, vitamins and precision actives: how GleySy® builds its molecular combinations, active by active.

Double hélice d'ADN et molécules translucides — la recherche en biotechnologie cutanée GleySy®
An active is only worth what it enables in the others.

For a long time, professional skincare progressed through concentration: more active, more promise. That era is behind us.

Skin biotechnology has moved the question. It no longer asks how much, but what — with what, at which level, and in which order. That shift is the heart of GleySy® expertise.

PDRN, biotechnology brought into skincare

Polydeoxyribonucleotides — PDRN — are purified, fractionated DNA fragments obtained through strictly controlled biotechnology processes. Their interest in professional cosmetics lies in their very nature: they are molecules of the living, not synthetic molecules designed to imitate it.

GleySy® formulates them under the name Sodium DNA in RICH PDRN, where they never work alone: amino acids, L-lactic acid and hyaluronic acid complete the architecture.

This combination is not a stack. The amino acids supply the elementary material, L-lactic acid sustains surface renewal, hyaluronic acid establishes the hydrated medium in which the whole operates. Removing one of them does not diminish the formula: it unbalances it.

Its signature: biotechnology set within a complete formula, never sold as an isolated active.

Rich PDRN GleySy® — PDRN complex — Box of 5 × 10 mlPDRN complexRich PDRNProfessional complex combining Sodium DNA, amino acids, lactic acid and hyaluronic acid.Discover RICH PDRN

Biomimetic peptides — a language, not a force

A peptide is a short sequence of amino acids. Its distinctive quality is not its power: it is its specificity. Where a conventional active works through mass, a peptide works through shape.

Biomimetic means exactly that: reproducing a sequence the skin already knows how to read. A matter of vocabulary, not of dose.

RICH BTX combines neuropeptides with hyaluronic acid, for the expression areas where facial mobility marks the skin relief fastest.

A cosmetic peptide formulation: its action is not comparable to that of a botulinum toxin injection and makes no claim to replace it.

Its signature: the precision of a sequence, where concentration is no longer enough.

Rich BTX GleySy® — Peptide complex — Box of 5 × 5 mlPeptide complexRich BTXProfessional complex of peptides and hyaluronic acid.Discover RICH BTX

Vitamins — the environment of the result

A high-performing active in a depleted environment delivers nothing. That is the purpose of vitamin complexes: preparing the ground rather than forcing the way.

VITAMIN BOOST + HA brings together B and K vitamins, retinol, hyaluronic acid and natural moisturising factors. Three complementary registers meet there: supply, retention, and the skin’s own moisturising factor.

Its signature: a formula that tends to the environment as much as to the target.

Vitamin Boost + HA GleySy® — Vitamin complex — Box of 5 × 10 mlVitamin complexVitamin Boost + HAProfessional complex combining vitamins, hyaluronic acid and natural moisturising factors.Discover VITAMIN BOOST + HA

Precision actives for the complexion

Complexion evenness is the ground where combining actives makes the most sense. Pigmentation does not arise from a single mechanism: melanin synthesis, metallic cofactors, surface renewal and oxidative stress all play a part.

One active alone can therefore cover only part of it. WHITENING BOOST brings together eleven cosmetic actives, each with a distinct function:

  • Niacinamide, tranexamic acid, alpha-arbutin and kojic acid — the pigment synthesis pathway.
  • Phytic acid — chelation of metallic cofactors.
  • Lactobionic and mandelic acids — gentle surface renewal.
  • Ethylated vitamin C and carnosine — antioxidant protection.
  • Nonapeptide-1 and hyaluronic acid — peptide precision and application comfort.

Eleven actives are not worth more than three by their number. They are worth it because none is redundant.

Its signature: the most accomplished demonstration of the GleySy® multi-active principle.

Whitening Boost GleySy® — Even complexion — Box of 5 × 10 mlEven complexionWhitening BoostMulti-active complex designed to promote a visibly more even complexion.Discover WHITENING BOOST

RICH MELANOVA — precision applied to the complexion

RICH MELANOVA Serum and RICH MELANOVA Cream extend the in-practice work into daily care: tranexamic acid, niacinamide, alpha-arbutin and kojic acid, in two textures and two moments of the routine.

The serum adds PAD and vitamins B3 and B5; the cream, carnosine and hyaluronic acid — the same formulation intent, served by two galenic forms.

Rich Melanova Serum GleySy® — Anti-dark-spot serum — 30 mlAnti-dark-spot serumRich Melanova SerumCosmetic serum intended to promote radiance and visual complexion evenness.Discover RICH MELANOVA Serum

Combination as a method

Combining actives is not adding them up. A combination depends on the physicochemical compatibility of the molecules, on the pH of the final formula, on the stability of the whole over time and on the real availability of each component.

That work — invisible on an INCI list — is what separates a formulation from a juxtaposition.

At GleySy®, an active enters a formula because it is missing from it. Never because it sells.

Three ranges, a single method

The same logic governs professional hydration: our multi-fraction hyaluronic acid technology sets out the principle, fraction by fraction.

And it governs the peels, where precision rests on pH and on the nature of the acids: the science of GleySy® peeling. Three professional ranges, a single formulation requirement.

GleySy® — biotechnology in the service of cutaneous precision.

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